Ronald Melzack, a Canadian psychologist, and Patrick David Wall, a British physician, came up with a law in 1962 with regard to the perception of corporeal pain. It is known as Gate control law of Pain. The have tried to illustrate the formula of transmission of signals to the brain with regard to the presence of pain.
The nerves that do not send pain signals called nonnociceptive fibers are 'Ab' fibers and inhibit signals coming from pain fibers. There are two kinds of fibers that bring signals to the brain. Myelinated 'Ad' fiber is thick and carries massage of intense pain fast to the brain. 'C' fiber is unmyelinated and small and carries long term and throbbing pain slowly.
Baby Gate
The angle neuron is the one that sends the signal to the brain. When there is no input either at the small nerve fibers or at the large nerve fibers, the inhibitory neuron Ab prevents the angle neuron from sending any signal to the brain. Gate is closed. When large fiber stimulation takes place, both the inhibitory neuron and angle neuron get stimulated and the inhibitory neuron Ab prevents the angle neuron from sending signals to the brain. Gate is closed.
When small fiber stimulation takes place, inhibitory neuron Ab is inactive. Hence, angle neuron sends signals to the brain about pain. In this condition the gate is open. Gate law explains that the stimulus that activates nonnociceptive nerves can inhibit pain.
Brain controls the degree of pain that is perceived, which stimuli have to be ignored and which one to be accepted. This way brain can be trained to switch off types of pains which are not useful. This law has helped in understanding the way brain perceives pain. Pain control worked out based on this law has been beneficial in providing relief to patients.
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